anti-TSLP antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TSLP
  • 反应物种: Hu
  • 应用: ELISA, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TSLP
  • 抗原物种: Human
  • 抗原: E. coli derived recombinant Human TSLP.(MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQ)
  • Brand:
CAT.NO. : ARG66120
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TSLP
反应物种Hu
应用ELISA, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TSLP
抗原物种Human
抗原E. coli derived recombinant Human TSLP.
(MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQ)
偶联标记Un-conjugated
別名Thymic stromal lymphopoietin
应用说明
应用建议
应用推荐稀释比
ELISASandwich: 0.5 - 2.0 µg/ml with ARG66121 as a detection antibody
IHC-P0.125 µg/ml
WB0.1 - 0.2 µg/ml
应用说明IHC-P: Antigen Retrieval: Boil tissue section in Sodium Citrate buffer (pH 6.0) followed by cooling at RT for 20 min.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 85480 Human TSLP

Swiss-port # Q969D9 Human Thymic stromal lymphopoietin

基因名称TSLP
全名thymic stromal lymphopoietin
背景介绍This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
生物功能Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. [UniProt]
预测分子量18 kDa
检测图片 (4)
  • ARG66120 anti-TSLP antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded sections of Human prostate. The recommended ARG66120 anti-TSLP antibody concentration is 0.125 µg/ml with an overnight incubation at 4°C. An HRP-labeled polymer detection system was used with a DAB chromogen. Antigen Retrieval: Boil tissue section in Sodium Citrate buffer (pH 6.0) followed by cooling at RT for 20 min.

  • ARG66120 anti-TSLP antibody WB image

    Western blot: 250 - 0.24 ng of Human TSLP stained with ARG66120 anti-TSLP antibody, under non-reducing conditions.

  • ARG66120 anti-TSLP antibody standard curve image

    Sandwich ELISA: ARG66120 anti-TSLP antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG66121 anti-TSLP antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.

  • ARG66120 anti-TSLP antibody WB image

    Western blot: 250 - 0.24 ng of Human TSLP stained with ARG66120 anti-TSLP antibody, under reducing conditions.

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