anti-U2AF1L4 antibody
CAT.NO. : ARG64793
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概述
产品描述 | Goat Polyclonal antibody recognizes U2AF1L4 |
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反应物种 | Hu |
预测物种 | Ms, Rat, Dog |
应用 | WB |
特异性 | This antibody is expected to recognise both reported isoforms (NP_001035515.1 and NP_659424.2). No cross-reactivity with U2AF1 expected. |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | U2AF1L4 |
抗原物种 | Human |
抗原 | C-EDGERAVAELSNR |
偶联标记 | Un-conjugated |
別名 | RNU2; U2 auxiliary factor 26; U2AF1-like 4; Splicing factor U2AF 26 kDa subunit; U2; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2AF1L3; U2AF1L3V1; U2AF1-like protein 3; U2af26; U2AF1RS3; U2AF1-RS3 |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q8WU68 Human Splicing factor U2AF 26 kDa subunit |
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基因名称 | U2AF1L4 |
全名 | U2 small nuclear RNA auxiliary factor 1-like 4 |
生物功能 | RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity). [UniProt] |
研究领域 | Gene Regulation antibody |
预测分子量 | 26 kDa |
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