anti-UACA antibody [UACA/1222]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [UACA/1222] recognizes UACA
  • 反应物种: Hu, Ms
  • 应用: WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: UACA/1222
  • 同位型: IgG1, kappa
  • 靶点名称: UACA
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56195
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Product Details
概述
产品描述Mouse Monoclonal antibody [UACA/1222] recognizes UACA
反应物种Hu, Ms
应用WB
宿主Mouse
克隆Monoclonal
克隆号UACA/1222
同位型IgG1, kappa
靶点名称UACA
抗原物种Human
抗原Recombinant human UACA protein.
偶联标记Un-conjugated
別名Uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING
应用说明
应用建议
应用推荐稀释比
WB0.5 - 1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA.
抗菌剂0.05% Sodium azide
稳定剂0.1 mg/ml BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 55075 Human UACA

GeneID: 72565 Mouse UACA

Swiss-port # Q8CGB3 Mouse Uveal autoantigen with coiled-coil domains and ankyrin repeats

Swiss-port # Q9BZF9 Human Uveal autoantigen with coiled-coil domains and ankyrin repeats

基因名称UACA
全名uveal autoantigen with coiled-coil domains and ankyrin repeats
生物功能Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation (By similarity). [UniProt]
细胞定位Nuclear membrane
预测分子量163 kDa
检测图片 (1)
  • ARG56195 anti-UACA antibody [UACA/1222] WB image

    Western blot: A549 cell lysate stained with ARG56195 anti-UACA antibody [UACA/1222].

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