anti-ZPR1 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes ZPR1
  • 反应物种: Hu
  • 应用: IHC-P, IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: ZPR1
  • 抗原物种: Human
  • 抗原表位: VRYTLSVRAL EDMNREVVKT DSAATRIPEL DFEIPAFSQK GALTTVEGLI TRAISGLEQD QPARRANKDA TAERIDEFIV KLKELKQVAS PFTLIIDDPS GNSFVENPHA PQKDDALVIT HYNRTRQQEE MLGLQEEAPA EKPEEEDLRN EVLQFSTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS GGAVEPLGTR ITLHITDASD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD IRELVTKNPF TLGDSSNPGQ TERLQEFSQK MDQIIEGNMK AHFIMDDPAG NSYLQNVYAP EDDPEMKVER
  • Brand:
CAT.NO. : ARG44995
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes ZPR1
反应物种Hu
应用IHC-P, IP
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称ZPR1
抗原物种Human
抗原表位VRYTLSVRAL EDMNREVVKT DSAATRIPEL DFEIPAFSQK GALTTVEGLI TRAISGLEQD QPARRANKDA TAERIDEFIV KLKELKQVAS PFTLIIDDPS GNSFVENPHA PQKDDALVIT HYNRTRQQEE MLGLQEEAPA EKPEEEDLRN EVLQFSTNCP ECNAPAQTNM KLVQIPHFKE VIIMATNCEN CGHRTNEVKS GGAVEPLGTR ITLHITDASD MTRDLLKSET CSVEIPELEF ELGMAVLGGK FTTLEGLLKD IRELVTKNPF TLGDSSNPGQ TERLQEFSQK MDQIIEGNMK AHFIMDDPAG NSYLQNVYAP EDDPEMKVER
偶联标记Un-conjugated
別名ZPR1; ZPR1 Zinc Finger; Zinc Finger Protein 259; ZNF259; Zinc Finger Protein ZPR1; GKAF
应用说明
应用建议
应用推荐稀释比
IHC-P1:200
IP1:100
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
抗菌剂0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 8882 Human ZPR1

Swiss-port # O75312 Human Zinc finger protein ZPR1

基因名称ZPR1
全名ZPR1 Zinc Finger
背景介绍The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
生物功能Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H2O2-induced neuronal cell death. [Uniprot]
细胞定位Cell projection, Cytoplasm, Nucleus. [Uniprot]
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