FGF8 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes FGF8
  • 反应物种: Hu, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: FGF8
  • 抗原物种: Human
  • 抗原: Recombinant protein corresponding to Q23-R233 of Human FGF8.
  • Brand:
CAT.NO. : ARG43745
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes FGF8
反应物种Hu, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称FGF8
抗原物种Human
抗原Recombinant protein corresponding to Q23-R233 of Human FGF8.
偶联标记Un-conjugated
Protein Full nameFibroblast growth factor 8
別名Fibroblast growth factor 8; HH6; AIGF; FGF-8; HBGF-8; KAL6; Heparin-binding growth factor 8; Androgen-induced growth factor
应用说明
应用建议
应用推荐稀释比
WB1:1000 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量26-30 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 2253 Human FGF8

Swiss-port # P55075 Human Fibroblast growth factor 8

基因名称FGF8
全名fibroblast growth factor 8 (androgen-induced)
背景介绍The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008]
生物功能Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Plays a role in neurite outgrowth in hippocampal cells. [UniProt]
细胞定位Secreted. [UniProt]
预测分子量27 kDa
翻译后修饰Glycoprotein
检测图片 (1)
  • ARG43745 anti-FGF8 antibody WB image

    Western blot: Rat ovary tissue, HeLa cell, human placenta tissue lysates stained with ARG43745 anti-FGF8 antibody at 0.5 ug/mL dilution.

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