Human beta Catenin ELISA Kit
CAT.NO. : ARG83441
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概述
产品描述 | ARG83441 Human beta Catenin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human beta Catenin in Serum, plasma and cell culture supernatants., Tissue Homogenates |
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反应物种 | Hu |
应用 | ELISA |
靶点名称 | beta Catenin |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 6.4 pg/ml |
样品类型 | Serum, plasma and cell culture supernatants., Tissue Homogenates |
标准范围 | 15.6 - 1000 pg/ml |
样本量 | 100 µl |
精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
別名 | CTNNB; armadillo; MRD19; Catenin beta-1; Beta-catenin |
应用说明
检测时间 | 3.5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CTNNB1 |
全名 | Catenin Beta 1 |
背景介绍 | Catenin is one of the key downstream effectors in the Wnt signaling pathway. It has been implicated to play an important role in early embryonic development and tumorigenesis. β-catenin can be destabilized by GSK-3β or other kinases by phosphorylating it at serines 33, 37, 45 and threonine 41. Mutations of these phosphorylation sites in β-catenin have been found in many tumor cell lines. |
生物功能 | Key downstream component of the canonical Wnt signaling pathway |
细胞定位 | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse |
产品亮点 | Related products: beta Catenin antibodies; beta Catenin Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Besides tumor suppression, what’s p53 busy for during embryogenesis? Wnt / beta-catenin signaling for gastric fundus specification |
翻译后修饰 | Acetylation, Glycoprotein, Phosphoprotein, S-nitrosylation, Ubl conjugation |
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