Human Cardiac Troponin I ELISA Kit
Key features and details
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- 反应物种:
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- 偶联标记:
- 偶联标记说明:
- 灵敏度:
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CAT.NO. : ARG81144
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Product Details
概述
| 产品描述 | ARG81144 Human Cardiac Troponin I ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Cardiac Troponin I in serum. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | Cardiac Troponin I |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 2.0 ng/ml |
| 样品类型 | Serum |
| 标准范围 | 2 - 75 ng/ml |
| 样本量 | 100 µl |
| 別名 | RCM1; cTnI; Cardiac troponin I; TNNC1; CMD1FF; CMD2A; Troponin I, cardiac muscle; CMH7 |
应用说明
| 检测时间 | ~ 2.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TNNI3 |
| 全名 | troponin I type 3 (cardiac) |
| 背景介绍 | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008] |
| 生物功能 | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [UniProt] |
| 产品亮点 | Related products: Troponin antibodies; Troponin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction (By similarity). Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). |
检测图片 (1)
ARG81144 Human Cardiac Troponin I ELISA Kit standard curve image
ARG81144 Human Cardiac Troponin I ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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