Human Cardiac Troponin I (High sensitive) ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG82201
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Product Details
概述
| 产品描述 | ARG82201 Human Cardiac Troponin I (High sensitive) ELISA Kit is a high sensitive Enzyme Immunoassay kit for the quantification of Human Cardiac Troponin I in serum, plasma and cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Not react with the following recombinant human proteins: Adiponectin, ApoAI, BMP1, BMP2, BMP3, BMP4, BMP5, BMP7, CCL2, CCL4, CCL5, CRP, HGF, HSP27, IL1 beta, IL1RA, IL1 alpha, IL1RI, IL2, IL4, IL5, IL6, IL6R, IL8, IL12, IL13, IL15, IL17C, IL21, IL23, IFN beta, IFN gamma, PDGF, PLA2G7, prolactin, serpin E1, TGF beta 1, TGF beta 2, TGF beta 3, TLR1, TLR2, TL3, TLR9, TNF alpha, TNF RI, TNF RII, VEGF, VEGF R1. |
| 靶点名称 | Cardiac Troponin I |
| 偶联标记 | HRP |
| 偶联标记说明 | Read at 450 nm. |
| 灵敏度 | 18 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 93.75 - 6000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 5% Inter-Assay CV: 8% |
| 別名 | RCM1; cTnI; Cardiac troponin I; TNNC1; CMD1FF; CMD2A; Troponin I, cardiac muscle; CMH7 |
应用说明
| 检测时间 | 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TNNI3 |
| 全名 | troponin I type 3 (cardiac) |
| 背景介绍 | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008] |
| 生物功能 | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [UniProt] |
| 产品亮点 | Related products: Troponin antibodies; Troponin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Phosphorylated at Ser-42 and Ser-44 by PRKCE; phosphorylation increases myocardium contractile dysfunction (By similarity). Phosphorylated at Ser-23 and Ser-24 by PRKD1; phosphorylation reduces myofilament calcium sensitivity. Phosphorylated preferentially at Thr-31. Phosphorylation by STK4/MST1 alters its binding affinity to TNNC1 (cardiac Tn-C) and TNNT2 (cardiac Tn-T). [UniProt] |
检测图片 (1)
ARG82201 Human Cardiac Troponin I (High sensitive) ELISA Kit standard curve image
ARG82201 Human Cardiac Troponin I (High sensitive) ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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