Human CD226 ELISA Kit
CAT.NO. : ARG83246
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概述
产品描述 | ARG83246 Human CD226 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD226 in Serum, Plasma and Cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | There is no detectable cross-reactivity with other relevant proteins. |
靶点名称 | CD226 |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 7 pg/ml |
检测范围 | 93.7 pg/ml - 6,000 pg/ml |
样品类型 | Serum, Plasma and Cell culture supernatants |
精确 | Intra-Assay CV: 6.0% Inter-Assay CV: 6.9% |
別名 | TLiSA1; CD antigen CD226; PTA1; CD226 antigen; DNAM-1; DNAX accessory molecule 1; DNAM1 |
应用说明
检测时间 | ~ 5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CD226 |
全名 | CD226 molecule |
背景介绍 | This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] |
生物功能 | Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell (PubMed:8673704). Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding (PubMed:26755705). [UniProt] |
细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
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