Human CD49a / Integrin alpha 1 ELISA Kit
CAT.NO. : ARG83308
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概述
产品描述 | ARG83308 Human CD49a / Integrin alpha 1 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CD49a / Integrin alpha 1 in Serum, Plasma and Cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | There is no detectable cross-reactivity with other relevant proteins. |
靶点名称 | CD49a / Integrin alpha 1 |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 80 pg/ml |
检测范围 | 156 pg/ml - 10,000 pg/ml |
样品类型 | Serum, Plasma and Cell culture supernatants |
精确 | Intra-Assay CV: 3.7% Inter-Assay CV: 4.4% |
別名 | VLA-1; CD49a; Integrin alpha-1; Laminin and collagen receptor; VLA1; CD antigen CD49a; CD49 antigen-like family member A |
应用说明
检测时间 | ~ 5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | ITGA1 |
全名 | integrin, alpha 1 |
背景介绍 | This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008] |
生物功能 | Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. [UniProt] |
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