Human Copeptin ELISA Kit

Key features and details

  • 产品描述: ARG81384 Human Copeptin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Copeptin in serum and plasma.
  • 反应物种: Hu
  • 应用: ELISA
  • 特异性: Cross-Reactivity: Not react with Copeptin (Rat), Vasopressin (Human, Rat, Mouse, Canine), Angiotensin II (Human, Rat, Mouse, Canine), Angiotensin I (Human, Rat, Mouse, Porcine Canine), Endothelin-1 (Human, Rat, Mouse, Porcine, Bovine, Canine) and Urotensin II (Human).
  • 靶点名称: Copeptin
  • 偶联标记: HRP
  • 偶联标记说明: Substrate: TMB and read at 450 nm.
  • 灵敏度: 0.12 ng/ml
  • 检测范围: 0.12 - 2.71 ng/ml
  • Brand:
CAT.NO. : ARG81384
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Product Details
概述
产品描述ARG81384 Human Copeptin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Copeptin in serum and plasma.
反应物种Hu
应用ELISA
特异性Cross-Reactivity: Not react with Copeptin (Rat), Vasopressin (Human, Rat, Mouse, Canine), Angiotensin II (Human, Rat, Mouse, Canine), Angiotensin I (Human, Rat, Mouse, Porcine Canine), Endothelin-1 (Human, Rat, Mouse, Porcine, Bovine, Canine) and Urotensin II (Human).
靶点名称Copeptin
偶联标记HRP
偶联标记说明Substrate: TMB and read at 450 nm.
灵敏度0.12 ng/ml
检测范围0.12 - 2.71 ng/ml
样品类型Serum and plasma
标准范围0.01 - 100 ng/ml
样本量50 µl
精确Intra-assay: less than 10%
Inter-assay:
別名Arginine-vasopressin; Vasopressin-neurophysin 2-copeptin; VP; AVRP; AVP-NPII; Neurophysin-II; ARVP; ADH
应用说明
检测时间~ 4 hours
属性
形式96 well
存放说明Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项For laboratory research only, not for drug, diagnostic or other use. This kit cannot ship or deliver to addresses in the following countries: Argentina, Austria, Belgium, China, France, Germany, Hungary, India, Italy, Japan, Liechtenstein, Luxembourg, Mexico, Spain, Switzerland, United Kingdom. Due to the assay method performed by this product is covered by Patent No. EP1738178 in these countries.
生物信息
数据库连接

GeneID: 551 Human AVP

Swiss-port # P01185 Human Vasopressin-neurophysin 2-copeptin

基因名称AVP
全名arginine vasopressin
背景介绍This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq, Mar 2010]
生物功能Neurophysin 2 specifically binds vasopressin.

Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. [UniProt]
产品亮点Related products:
Copeptin antibodies; Copeptin ELISA Kits; Copeptin Duos / Panels;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
检测图片 (1)
  • ARG81384 Human Copeptin ELISA Kit standard curve image

    ARG81384 Human Copeptin ELISA Kit results of a typical standard run with optical density reading at 450 nm.

参考文献

Prognostic Utility of Novel Biomarkers in Acute-on-chronic Liver Failure (ACLF) Associated with Hepatitis B: A Multicenter Prospective Study.

ELISA / Human

Zhao Ruihong et al.
Hepatol Res.,  (2018)

publication_link

 

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