Human CXCL1 / GRO alpha ELISA Kit
CAT.NO. : ARG83027
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概述
产品描述 | ARG83027 Human CXCL1 / GRO alpha ELISA Kitis an Enzyme Immunoassay kit for the quantification of Human CXCL1 / GRO alpha in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | Not cross-reacts with: Human GRO beta, IL8, RANTES, ENA78, MIP1 alpha, MIP1 beta, NAP2, MCP-1. Mouse KC, MIP1alpha, MIP1 beta, MIP2. Rat CINC1. |
靶点名称 | CXCL1 / GRO alpha |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
Protein Full name | Growth-regulated alpha protein |
灵敏度 | 15.6 pg/ml |
样品类型 | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
标准范围 | 31.3 - 2000 pg/ml |
样本量 | 100 µl |
精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
別名 | CXCL1, C X C Motif Chemokine Ligand , SCYB, NAP-3, MGSA A, GROa, GRO1, MGSA, Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha), GRO1 Oncogene (Melanoma Growth Stimulating Activity, Alpha), Melanoma Growth Stimulating Activity, Alpha, Neutrophil-Activating Protein 3, Growth-Regulated Alpha Protein, Fibroblast Secretory Protein, C-X-C Motif Chemokine , GRO-Alpha(1-73), FSP, GRO1 Oncogene (Melanoma Growth-Stimulating Activity), Melanoma Growth Stimulatory Activity Alpha, Melanoma Growth Stimulatory Activity, MGSA Alpha, GROA, GRO |
应用说明
检测时间 | ~ 4 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CXCL1 |
全名 | C-X-C Motif Chemokine Ligand 1 |
背景介绍 | This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014] |
生物功能 | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. [UniProt] |
细胞定位 | Secreted. [UniProt] |
产品亮点 | Related products: CXCL1 antibodies; CXCL1 ELISA Kits; Related news: Immune signaling protein TLR4 has opposing roles in breast cancer development New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
翻译后修饰 | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. [UniProt] |
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