Human DBP / Vitamin D binding protein ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
- 标准范围:
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Brand:
CAT.NO. : ARG82260
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Product Details
概述
| 产品描述 | ARG82260 Human DBP / Vitamin D binding protein ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human DBP / Vitamin D binding protein in serum and plasma. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 靶点名称 | DBP / Vitamin D binding protein |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 3 ng/ml |
| 样品类型 | Serum and plasma. |
| 标准范围 | 6.25 - 200 ng/ml |
| 样本量 | 100 µl |
| 別名 | GRD3; DBP/GC; HEL-S-51; VDBG; VDB; Gc-globulin; DBP; VDBP; Vitamin D-binding protein; Group-specific component |
应用说明
| 检测时间 | ~ 1.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GC |
| 全名 | group-specific component (vitamin D binding protein) |
| 背景介绍 | The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] |
| 生物功能 | Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: DBP antibodies; DBP ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Allele GC*1S is O-glycosylated at Thr-436 (PubMed:20079467). The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and galactose leaving an O-linked N-acetyl-galactosamine. This conversion is thought to produce a macrophage-activating factor (Gc-MAF). Only a minor proportion of plasma GC is O-glycosylated (PubMed:17360250). The potential N-glycosylation site predicted at Asn-288 is thought to be nonglycosylated. [UniProt] |
检测图片 (1)
ARG82260 Human DBP / Vitamin D binding protein ELISA Kit standard curve image
ARG82260 Human DBP / Vitamin D binding protein ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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