Human FGF10 recombinant protein (Active) (His-tagged, C-ter)
CAT.NO. : ARG70116
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概述
产品描述 | E. coli expressed, His-tagged (C-ter) Active Human FGF10 recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | FGF10 |
物种 | Human |
A.A. 序列 | Leu40 - Ser208 |
表达系统 | E. coli |
生物活性 | Active |
活性说明 | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is1.2 x 10^5 IU/mg. |
別名 | Fibroblast growth factor 10; Keratinocyte growth factor 2; FGF-10 |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | >98% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.4) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | FGF10 |
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全名 | fibroblast growth factor 10 |
背景介绍 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008] |
生物功能 | Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing. [UniProt] |
细胞定位 | Secreted. [UniProt] |
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