Human FGF19 ELISA Kit
CAT.NO. : ARG83033
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概述
产品描述 | ARG83033 Human FGF19 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human FGF19 in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | Not cross-reacts with: Human bFGF, FGF-21, FGF R1 alpha,FGF-R1 beta, FGF-R2 alpha, FGF-R2 beta. Mouse FGF15, FGF21, FGF23, FGFR1 alpha, FGFR1 beta. RatFGF15, FGF21, FGF23, FGFR1 alpha, FGFR1 beta. |
靶点名称 | FGF19 |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
Protein Full name | Fibroblast growth factor 19 |
灵敏度 | 15.6 pg/ml |
样品类型 | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
标准范围 | 31.3 - 2000 pg/ml |
样本量 | 100 µl |
精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
別名 | FGF19, FGF 19,Fibroblast Growth Factor 19 |
应用说明
检测时间 | ~ 4 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | FGF19 |
全名 | Fibroblast Growth Factor 19 |
背景介绍 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008] |
生物功能 | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. [UniProt] |
细胞定位 | Secreted. [UniProt] |
产品亮点 | Related products: FGF19 antibodies; FGF19 ELISA Kits; FGF19 recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
翻译后修饰 | Disulfide bond. [UniProt] |
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