Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter)
CAT.NO. : ARG70390
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概述
产品描述 | E. coli expressed, His-tagged (C-ter) Human GIF / Gastric intrinsic factor recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | GIF / Gastric intrinsic factor |
物种 | Human |
A.A. 序列 | Met1 - Tyr417 |
表达系统 | E. coli |
Protein Full name | Cobalamin binding intrinsic factor |
別名 | CBLIF; Cobalamin Binding Intrinsic Factor; IFMH; INF; IF; TCN3; GIF; Gastric Intrinsic Factor (Vitamin B Synthesis); Gastric Intrinsic Factor; Intrinsic Factor |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | >98% (by SDS-PAGE) |
缓冲液 | PBS (pH 8.0) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | CBLIF |
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全名 | Cobalamin Binding Intrinsic Factor |
背景介绍 | This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. |
生物功能 | Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis. |
细胞定位 | Secreted |
翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein |
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