Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter)

Key features and details

  • 产品描述: E. coli expressed, His-tagged (C-ter) Human GIF / Gastric intrinsic factor recombinant protein
  • 应用: SDS-PAGE
  • 靶点名称: GIF / Gastric intrinsic factor
  • 物种: Human
  • A.A. 序列: Met1 - Tyr417
  • 表达系统: E. coli
  • Protein Full name: Cobalamin binding intrinsic factor
  • 別名: CBLIF; Cobalamin Binding Intrinsic Factor; IFMH; INF; IF; TCN3; GIF; Gastric Intrinsic Factor (Vitamin B Synthesis); Gastric Intrinsic Factor; Intrinsic Factor
  • Brand:
CAT.NO. : ARG70390
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Product Details
概述
产品描述E. coli expressed, His-tagged (C-ter) Human GIF / Gastric intrinsic factor recombinant protein
应用SDS-PAGE
靶点名称GIF / Gastric intrinsic factor
物种Human
A.A. 序列Met1 - Tyr417
表达系统E. coli
Protein Full nameCobalamin binding intrinsic factor
別名CBLIF; Cobalamin Binding Intrinsic Factor; IFMH; INF; IF; TCN3; GIF; Gastric Intrinsic Factor (Vitamin B Synthesis); Gastric Intrinsic Factor; Intrinsic Factor
属性
形式Powder
纯化说明Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度>98% (by SDS-PAGE)
缓冲液PBS (pH 8.0)
复溶It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
存放说明For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称CBLIF
全名Cobalamin Binding Intrinsic Factor
背景介绍This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.
生物功能Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.
细胞定位Secreted
翻译后修饰Disulfide bond, Glycoprotein, Phosphoprotein
检测图片 (1)
  • ARG70390 Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter) SDS-PAGE image

    SDS-PAGE analysis of  ARG70390 Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter)

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