Human HMGB2 recombinant protein (His-SUMO tagged, N-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- Protein Full name:
- 別名:
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Brand:
CAT.NO. : ARG70383
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Product Details
概述
| 产品描述 | HEK293 expressed, His-SUMO tagged (N-ter) Human HMGB2 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | HMGB2 |
| 物种 | Human |
| A.A. 序列 | Met1 - Pro187 |
| 表达系统 | HEK293 |
| Protein Full name | High mobility group protein B2 |
| 別名 | HMGB2; High Mobility Group Box 2; HMG2; High-Mobility Group (Nonhistone Chromosomal) Protein 2; High Mobility Group Protein B2; High Mobility Group Protein 2; HMG-2; High-Mobility Group Box 2 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | HMGB2 |
|---|---|
| 全名 | High Mobility Group Box 2 |
| 背景介绍 | This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. |
| 生物功能 | Proposed to be involved in the innate immune response to nucleic acids by acting as a promiscuous immunogenic DNA/RNA sensor which cooperates with subsequent discriminative sensing by specific pattern recognition receptors. |
| 细胞定位 | Chromosome, Cytoplasm, Nucleus, Secreted |
| 翻译后修饰 | Acetylation, Disulfide bond, Oxidation, Phosphoprotein |
检测图片 (1)
ARG70383 Human HMGB2 recombinant protein (His-SUMO tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70383 Human HMGB2 recombinant protein (His-SUMO tagged, N-ter)
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