Human IL18 binding protein recombinant protein (His-tagged)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- Protein Full name:
- 別名:
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Brand:
CAT.NO. : ARG70478
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Product Details
概述
| 产品描述 | HEK293 expressed, His-tagged Human IL18 binding protein recombinant protein. |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | IL18 binding protein |
| 物种 | Human |
| A.A. 序列 | Met1-Gly194 |
| 表达系统 | HEK293 |
| Protein Full name | Interleukin-18-binding protein |
| 別名 | IL18BP; Interleukin 18 Binding Protein; IL18BPa; MC51L-53L-54L Homolog Gene Product; Interleukin-18-Binding Protein; Tadekinig-Alfa; IL-18BP; FVH |
属性
| 形式 | Powder |
|---|---|
| 纯化 | >95% (by SDS-PAGE) |
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IL18BP |
|---|---|
| 全名 | Interleukin 18 Binding Protein |
| 背景介绍 | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |
| 生物功能 | Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. [Uniprot] |
检测图片 (1)
ARG70478 Human IL18 binding protein recombinant protein (His-tagged) SDS-PAGE image
SDS-PAGE analysis of ARG70478 Human IL18 binding protein recombinant protein (His-tagged).
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