Human IL36RN ELISA Kit
CAT.NO. : ARG83014
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概述
产品描述 | ARG83014 Human IL36RN ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human IL36RNin serum, plasma (heparin), ascites, urine and cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | Not cross-reacts with: Human IL1beta, IL1F7, IL1Ra, IL36 alpha, IL36 beta, IL36 gamma. Mouse IL-36Ra |
靶点名称 | IL36RN |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
Protein Full name | Interleukin-1 receptor antagonist protein |
灵敏度 | 0.078 ng/ml |
样品类型 | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
标准范围 | 0.156 - 10 ng/ml |
样本量 | 100 µl |
精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
別名 | IL1RN , Interleukin 1 Receptor Antagonis, ICIL-1RA, IL-1RN, IL1RA, IL1F3, IRAP, Interleukin-1 Receptor Antagonist Protein, IL1 Inhibito, MGC10430, IL-1ra, Intracellular Interleukin-1 Receptor Antagonist (IcIL-1ra), Intracellular Interleukin-1 Receptor Antagonist, Intracellular IL-1 Receptor Antagonist Type II, Type II Interleukin-1 Receptor Antagonist, Anakinr, IL-1ra3, MVCD4, DIRA |
应用说明
检测时间 | ~ 4 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P18510 Human Interleukin-1 receptor antagonist protein |
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基因名称 | IL1RN |
全名 | Interleukin 1 Receptor Antagonist |
背景介绍 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020] |
生物功能 | Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. [UniProt] |
细胞定位 | Cytoplasm, Secreted. [UniProt] |
翻译后修饰 | Disulfide bond, Glycoprotein. [Uniprot] |
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