Human IL9 recombinant protein (Active) (His-tagged, N-ter)
CAT.NO. : ARG70052
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概述
产品描述 | E. coli expressed, His-tagged (N-ter) Active Human IL9 recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | IL9 |
物种 | Human |
A.A. 序列 | Gln19 - Ile144 |
表达系统 | E. coli |
生物活性 | Active |
活性说明 | Determined by its ability to induce proliferation in MO7e cells. The ED50 for this effect is 5 x10^6 IU/ mg. |
別名 | IL-9; HP40; Interleukin-9; T-cell growth factor P40; Cytokine P40; P40 |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test. |
纯度 | >98% (by SDS-PAGE) |
缓冲液 | PBS (pH 8.0) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | IL9 |
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全名 | interleukin 9 |
背景介绍 | The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008] |
生物功能 | Supports IL-2 independent and IL-4 independent growth of helper T-cells. [UniProt] |
细胞定位 | Secreted. [UniProt] |
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