Human LTBR / Lymphotoxin beta Receptor recombinant protein (ECD) (Fc-His-tagged, C-ter)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- 別名:
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Brand:
CAT.NO. : ARG70324
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Product Details
概述
| 产品描述 | HEK293 expressed, Fc-His-tagged (C-ter) Human LTBR / Lymphotoxin beta Receptor recombinant protein (ECD). |
|---|---|
| 反应物种 | Hu |
| 应用 | Binding, SDS-PAGE |
| 靶点名称 | LTBR / Lymphotoxin beta Receptor (ECD) |
| 物种 | Human |
| A.A. 序列 | Gln31 - Met227 of Human LTBR / Lymphotoxin beta Receptor (NP_002333.1) with an Fc-6X His tag at the C-terminus. |
| 表达系统 | HEK293 |
| 別名 | TNF-RIII; LT-BETA-R; Tumor necrosis factor receptor superfamily member 3; TNF-R-III; TNFR-III; TNFR-RP; TNFR3; D12S370; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; TNFCR; Tumor necrosis factor receptor type III; Lymphotoxin-beta receptor; TNFR2-RP; CD18; TNFRSF3 |
应用说明
| 应用说明 | Binding activity test: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human LIGHT at 1µg/ml (100 µl/well) can bind Recombinant Human LTBR with a linear range of 14.3-57.4 ng/ml. |
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属性
| 形式 | Powder |
|---|---|
| 纯化说明 | 0.22 µm filter sterilized. Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P36941 Human Tumor necrosis factor receptor superfamily member 3 |
|---|---|
| 基因名称 | LTBR |
| 全名 | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| 背景介绍 | This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] |
| 生物功能 | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 47 kDa |
检测图片 (1)
ARG70324 Human LTBR / Lymphotoxin beta Receptor recombinant protein (ECD) (Fc-His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70324 Human LTBR / Lymphotoxin beta Receptor recombinant protein (ECD) (Fc-His-tagged, C-ter).
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