Human MMP7 Assay Kit
CAT.NO. : ARG82629
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概述
产品描述 | ARG82629 Human MMP7 Assay Kit is a detection kit for the quantification of Human MMP7 in serum, urine, tissue homogenates and cell culture supernatants. |
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反应物种 | Hu |
应用 | FuncSt |
特异性 | Measures endogenous active MMP7 (naturally occurring) or total active MMP7 (following activation with APMA). |
靶点名称 | MMP7 |
偶联标记说明 | Read at 405 nm. |
灵敏度 | 30 pg/ml for 3 hours incubation 4 pg/ml for 25 hours incubation |
检测范围 | 4 - 16000 pg/ml |
样品类型 | Serum, urine, tissue homogenates and cell culture supernatants. |
样本量 | 100 µl |
別名 | MMP-7; Uterine metalloproteinase; Matrix metalloproteinase-7; EC 3.4.24.23; Matrilysin; Matrin; Pump-1 protease; PUMP-1; MPSL1 |
应用说明
检测时间 | Overnight |
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属性
形式 | 96 well |
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存放说明 | Store the kit at -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | MMP7 |
全名 | matrix metallopeptidase 7 |
背景介绍 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] |
生物功能 | Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. [UniProt] |
细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
检测图片 (3)
ARG82629 Human MMP7 Assay Kit typical data demonstration image
ARG82629 Human MMP7 Assay Kit results of a typical data with optical density reading at 405 nm (after 3 hours incubation).
ARG82629 Human MMP7 Assay Kit typical data demonstration image
ARG82629 Human MMP7 Assay Kit results of a typical data with optical density reading at 405 nm (after 6 hours incubation).
ARG82629 Human MMP7 Assay Kit typical data demonstration image
ARG82629 Human MMP7 Assay Kit results of a typical data with optical density reading at 405 nm (after 25 hours incubation).
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