Human PGA5 recombinant protein (His-tagged, C-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- Protein Full name:
- 別名:
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Brand:
CAT.NO. : ARG70453
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Human PGA5 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | PGA5 |
| 物种 | Human |
| A.A. 序列 | Met1 - Ala388 |
| 表达系统 | E. coli |
| Protein Full name | Pepsin A-5 |
| 別名 | PGA5; Pepsinogen A5; Pepsinogen 5, Group I (Pepsinogen A); Pepsinogen-5; Pepsin A-5; Pepsin A; Pepsinogen-4 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | PGA5 |
|---|---|
| 全名 | Pepsinogen A5 |
| 背景介绍 | This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. |
| 生物功能 | Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond, Phosphoprotein, Zymogen |
检测图片 (1)
ARG70453 Human PGA5 recombinant protein (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70453 Human PGA5 recombinant protein (His-tagged, C-ter)
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