Microvascular Density Antibody Panel

Key features and details

  • 产品描述: Microvascular Density Antibody (MVD) Panel is an all-in-one solution to make angiogenesis research easy and economic. This antibody panel comprises the proliferation marker Ki-67 antibody, endothelial marker CD31 antibody, and mural cell markers Desmin and alpha-SMA antibodies. All the antibodies in this panel have excellent IHC performance. It is the best solution to examine the process of angiogenesis in tumor tissues and xenograft model.Related news:Angiogenesis & MVD Antibody Panels are released
  • 靶点名称: Microvascular Density
  • 別名: Microvascular Density antibody; CD31 antibody; Desmin antibody; Ki-67 antibody; alpha smooth muscle Actin antibody
  • Brand:
CAT.NO. : ARG30327
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Product Details
内含物
货号内含物名称宿主克隆性反应应用包装
ARG66347anti-Ki-67 antibody [SQab1897]Rabbit mAbHuIHC-P20 μl
ARG52748anti-CD31 antibodyRabbit pAbHu, Ms, Rat, PigICC/IF, IHC-FoFr , IHC-Fr, IHC-P, WB20 μl
ARG66200anti-Desmin antibody [SQab1722]Rabbit mAbHu, Ms, RatIHC-P, WB20 μl
ARG66381anti-alpha smooth muscle Actin antibody [SQab18108]Rabbit mAbHu, Ms, Rat, AGMK, Bov, Ctl, Dog, Pig, ZfshFACS, ICC/IF, IHC-Fr, IHC-P, WB20 μl
ARG65351Goat anti-Rabbit IgG antibody (HRP)Goat pAbRbELISA, IHC-P, WB50 μl
概述
产品描述Microvascular Density Antibody (MVD) Panel is an all-in-one solution to make angiogenesis research easy and economic. This antibody panel comprises the proliferation marker Ki-67 antibody, endothelial marker CD31 antibody, and mural cell markers Desmin and alpha-SMA antibodies. All the antibodies in this panel have excellent IHC performance. It is the best solution to examine the process of angiogenesis in tumor tissues and xenograft model.

Related news:
Angiogenesis & MVD Antibody Panels are released
靶点名称Microvascular Density
別名Microvascular Density antibody; CD31 antibody; Desmin antibody; Ki-67 antibody; alpha smooth muscle Actin antibody
属性
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
全名Antibody Panel for Microvascular Density
研究领域Angiogenesis antibody; MVD Antibody; Microvascular Density Antibody
检测图片 (22)
  • ARG52748 anti-CD31 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and Paraffin-embedded MDA-MB-231 (tumor xenograft study) stained with ARG52748 anti-CD31 antibody.
    Antigen Retrieval Buffer: Bond Epitope Retrieval Solution.

  • ARG66200 anti-Desmin antibody [SQab1722] WB image

    Western blot: 30 µg of MEF (negative control) and Mouse heart lysates stained with ARG66200 anti-Desmin antibody [SQab1722] at 1:5000 dilution.

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] IHC-Fr image

    Immunohistochemistry: Mouse liver and Mouse aorta stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:100 dilution.

    From Masahiro Terasawa et al. Cells (2023), doi: 10.3390/cells12222666, Fig. 2A.

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] WB image

    Western blot: 30 μg of NRK-49F cells treated with TGF beta 1 (10 ng/ml) for 0~48 hours. Cell lysates were stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:2000 dilution, overnight at 4°C.

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] ICC/IF image

    Immunofluorescence: NRK-49F cells treated with TGF beta 1 (10 ng/ml) for 0~48 hours. Cells were fixed with 4% PFA for 15 min at room temperature and permeabilizated by 0.5% Triton X-100. Cells were stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:200 dilution, overnight at 4°C.

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] FACS image

    Flow Cytometry: HeLa cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% TritonX-100 for 15 min. The cells were then stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] (red) at 1:100 dilution in 1x PBS/1% BSA for 30 min at 4°C, followed by Alexa Fluor® 488 labelled secondary antibody. Unlabelled sample (green) was used as a control.

  • ARG66200 anti-Desmin antibody [SQab1722] IHC-P image

    Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human colon tissue stained with ARG66200 anti-Desmin antibody [SQab1722] at 1:8000 dilution.

    Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0

  • ARG66347 anti-Ki-67 antibody [SQab1897] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human tonsil tissue stained with ARG66347 anti-Ki-67 antibody [SQab1897]. Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded placenta stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:2000 dilution. Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] WB image

    Western blot: 10 µg of HeLa, HaCat, 293, LnCap, PC-3 and T47D cell lysates stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:2000 dilution.

  • ARG52748 anti-CD31 antibody WB image

    Western blot: 30 µg of HUVEC lysate stained with ARG52748 anti-CD31 antibody at 1:500 dilution.

  • ARG66200 anti-Desmin antibody [SQab1722] IHC-P image

    Immunohistochemistry: Formalin‐fixed and paraffin‐embedded Human placenta tissue stained with ARG66200 anti-Desmin antibody [SQab1722] at 1:8000 dilution.

    Antigen retrieval: Heat mediated was performed using Tris/EDTA buffer pH 9.0

  • ARG66347 anti-Ki-67 antibody [SQab1897] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human esophageal cancer tissue stained with ARG66347 anti-Ki-67 antibody [SQab1897]. Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66347 anti-Ki-67 antibody [SQab1897] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human cervical cancer tissue stained with ARG66347 anti-Ki-67 antibody [SQab1897]. Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66347 anti-Ki-67 antibody [SQab1897] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human diffuse large B-cell lymphoma stained with ARG66347 anti-Ki-67 antibody [SQab1897]. Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66347 anti-Ki-67 antibody [SQab1897] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human esophageal cancer tissue stained with ARG66347 anti-Ki-67 antibody [SQab1897]. Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66347 anti-Ki-67 antibody [SQab1897] IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human tonsil tissue stained with ARG66347 anti-Ki-67 antibody [SQab1897]. Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0).

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] WB image

    Western blot: 10 µg of MDCK, MDBK, Pig heart, Zebrafish and Cos-7 lysates stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:2000 dilution.

  • ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] WB image

    Western blot: 10 µg of Mouse brain, Rat kidney and Rat liver lysates stained with ARG66381 anti-alpha smooth muscle Actin antibody [SQab18108] at 1:2000 dilution.

  • ARG52748 anti-CD31 antibody IHC-P image

    WB analysis of LLC xenograft mouse tumor tissue lysate stained with ARG52748 anti-CD31 antibody.

    Reproduced under the Creative Commons license from Xu Fei et al. J Exp Clin Cancer Res., (2018) 37:207 Doi: 10.1186/s13046-018-0878-0, Fig. 7C.

  • ARG52748 anti-CD31 antibody WB image

    WB analysis of LLC xenograft mouse tumor tissue lysate stained with ARG52748 anti-CD31 antibody.

    Reproduced under the Creative Commons license from Xu Fei et al. J Exp Clin Cancer Res., (2018) 37:207 Doi: 10.1186/s13046-018-0878-0, Fig. 7C.

  • ARG52748 anti-CD31 antibody IHC image

    Cryostat sections from Mouse Retinal stained with ARG52748 anti-CD31 antibody.

    Reproduced under the Creative Commons license from Lin Chin-I et al. July/August 2019, 6(4) ENEURO.0391-18.2019 1–17, Doi: 10.1523/ENEURO.0391-18.2019, Fig. 4 A-C.

参考文献

Expression of elastin, FBXW2, fibrillin-1, and α-smooth muscle actin in damaged blood vessels of bovine legs

ARG66381: IHC-P / Bovine

Mari Akiyama et al.
Preprint,  (2024)

publication_link

 

hr_line

Formononetin ameliorates isoproterenol induced cardiac fibrosis through improving mitochondrial dysfunction

ARG66381: WB / Mouse

Lei Qian et al.
Biomed Pharmacother.,  (2024)

publication_link

 

hr_line

Melatonin alleviates aging-related heart failure through melatonin receptor 1A/B knockout in mice

ARG66381: IHC-P / Mouse

Zhenyu Feng et al.
Heliyon,  (2024)

publication_link

 

hr_line

PCSK9 inhibitors ameliorate arterial stiffness in ACS patients: evidences from mendelian randomization, cohort studies and basic experiments

ARG66381: WB / Mouse

Linghao Xu et al.
Preprint,  (2024)

publication_link

 

hr_line

Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation

ARG66381: IHC-P / Mouse

Qiu-Yue Lin et al.
BBA - Molecular Basis of Disease,  (2024)

publication_link

 

hr_line

Vitamin E stabilizes iron and mitochondrial metabolism in pulmonary fibrosis

ARG66381: IHC-P / Mouse

Jing Chang et al.
Front Pharmacol.,  (2023)

publication_link

 

hr_line

circ-hnRNPU inhibits NONO-mediated c-Myc transactivation and mRNA stabilization essential for glycosylation and cancer progression

ARG52748: IHC-Fr / Human

Hongjun Li et al.
J Exp Clin Cancer Res.,  (2023)

publication_link

 

hr_line

Oral Administration of Rhamnan Sulfate from Monostroma nitidum Suppresses Atherosclerosis in ApoE-Deficient Mice Fed a High-Fat Diet

ARG66381: IFC-Fr / Mouse

Masahiro Terasawa et al.
Cells.,  (2023)

publication_link

 

hr_line

CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization

Mouse / ARG66381: IHC-P

Yun-Long Zhang et al.
J Adv Res.,  (2023)

publication_link

 

hr_line

Elastic Fibers and F-Box and WD-40 Domain-Containing Protein 2 in Bovine Periosteum and Blood Vessels

Cattle / ARG66381: IHC-P

Mari Akiyama et al.
Biomimetics (Basel).,  (2023)

publication_link

 

hr_line

ZLN005 Alleviates In Vivo and In Vitro Renal Fibrosis via PGC-1α-Mediated Mitochondrial Homeostasis

ARG66381: ICC/IF / Human

Pengfei Zhu et al.
Pharmaceuticals (Basel).,  (2022)

publication_link

 

hr_line

Inhibition of angiogenesis and tumor progression of MK-0429, an integrin αvβ3 antagonist, on oral squamous cell carcinoma

ARG66381: IHC-P / Human

Takayuki Nakagawa et al.
J Cancer Res Clin Oncol.,  (2022)

publication_link

 

hr_line

CT perfusion imaging can detect residual lung tumor early after radiofrequency ablation: a preliminary animal study on both tumoral and peri-tumoral region assessment

ARG52748: IHC-P / Rabbit

Zenghui Cheng et al.
J Thorac Dis.,  (2022)

publication_link

 

hr_line

Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4

ARG52748: IHC-P / Human

Fan Yang et al.
J Cell Mol Med.,  (2022)

publication_link

 

hr_line

Blocking VCAM-1 ameliorates hypertensive cardiac remodeling by impeding macrophage infiltration

ARG66381: IHC-P / Mouse

Ze-Yang Qiu  et al.
Front Pharmacol,  (2022)

publication_link

 

hr_line

Inhibition of Angiogenesis and Tumor Progression of Mk-0429, an Integrin Αvβ3 Antagonist, on Oral Squamous Cell Carcinoma

ARG66381: IHC-P / Human

Takayuki Nakagawa et al.
Research Square,  (2022)

publication_link

 

hr_line

Partial Reconstruction of Uterus Cervix in Rat by Decellularized Human Uterine Cervical Scaffold Combined with Adipose-Derived Stem Cells (ADSCs)

ARG52748: IHC-P / Mouse

Yuqi Li  et al.
J Immunol Res,  (2022)

publication_link

 

hr_line

Small Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhanced Proangiogenic Potential of Cardiac Fibroblasts via Angiopoietin-Like 4

ARG52748: WB / Human

Jiejie Li et al.
Stem Cells Int.,  (2022)

publication_link

 

hr_line

"Two-birds-one-stone" colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis

ARG66381: WB / Mouse

Jiaxin Zhang et al.
J Nanobiotechnology,  (2022)

publication_link

 

hr_line

Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy

ARG52748: IHC-P / Mouse

Lili Liu et al.
Mater Today Bio.,  (2022)

publication_link

 

hr_line

G6PD-NF-κB-HGF Signal in Gastric Cancer-Associated Mesenchymal Stem Cells Promotes the Proliferation and Metastasis of Gastric Cancer Cells by Upregulating the Expression of HK2

ARG52748: IHC-P / Mouse

Bin Chen et al.
Front Oncol,  (2021)

publication_link

 

hr_line

Additive Antiproliferative and Antiangiogenic Effects of Metformin and Pemetrexed in a Non-Small-Cell Lung Cancer Xenograft Model.

ARG52748: IHC-P / Mouse

Jiun-Long Wang et al.
Front Cell Dev Biol.,  (2021)

publication_link

 

hr_line

VEGF-C/VEGFR-3 axis protects against pressure-overload induced cardiac dysfunction through regulation of lymphangiogenesis.

ARG66381, ARG52748: IHC-P / Mouse

Qiu-Yue Lin et al.
Clin Transl Med.,  (2021)

publication_link

 

hr_line

Heterogeneous microenvironmental stiffness regulates pro-metastatic functions of breast cancer cells

ARG52748: IHC-P / Mouse

Chun Liu et al.
Acta Biomater.,  (2021)

publication_link

 

hr_line

Exploring the mechanism of Bushenhuoxue formula acting on postmenopausal osteoporosis via network pharmacology and experimental validation.

ARG52748: IHC-P / Mouse

Chunhai Ke et al.
Preprint.,  (2021)

publication_link

 

hr_line

pH and Glucose Dual-Responsive Injectable Hydrogels with Insulin and Fibroblasts as Bioactive Dressings for Diabetic Wound Healing

ARG52748: IHC-P / Rat

Lingling Zhao et al.
ACS Appl Mater Interfaces.,  (2021)

publication_link

 

hr_line

NIR-cleavable drug adducts of gold nanostars for overcoming multidrug-resistant tumors.

ARG52748: IHC-Fr / Mouse

Andrea C Del Valle et al.
Biomater Sci.,  (2020)

publication_link

 

hr_line

Amygdalin Promotes Fracture Healing through TGF- β/Smad Signaling in Mesenchymal Stem Cells.

ARG52748: IHC-P / Mouse

Jun Ying et al.
Stem Cells Int.,  (2020)

publication_link

 

hr_line

Platelet-rich plasma promotes bone formation, restrains adipogenesis and accelerates vascularization to relieve steroids-induced osteonecrosis of the femoral head.

ARG52748: IHC-P / Rat

Hui-Hui Xu et al.
Platelets.,  (2020)

publication_link

 

hr_line

Bushenhuoxue formula accelerates fracture healing via upregulation of TGF-β/Smad2 signaling in mesenchymal progenitor cells.

ARG52748: IHC-P / Mouse

Hu Songfeng et al.
Phytomedicine.,  (2020)

publication_link

 

hr_line

Peripheral Blood Stem Cell Therapy Does Not Improve Outcomes of Femoral Head Osteonecrosis With Cap-Shaped Separated Cartilage Defect.

ARG52748: IHC-P / Human

Ying Jun et al.
J Orthop Res.,  (2019)

publication_link

 

hr_line

Therapeutic targeting of circ-CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression.

ARG52748: IHC-P / Human

Huanhuan Li et al.
EMBO Mol Med.,  (2019)

publication_link

 

hr_line

N-acetyl cysteine-loaded graphene oxide-collagen hybrid membrane for scarless wound healing.

ARG52748: IHC-P / Rat

Li Jialun et al.
Theranostics.,  (2019)

publication_link

 

hr_line

Blue Light Promotes Neurite Outgrowth of Retinal Explants in Postnatal ChR2 Mice.

ARG52748: IHC-Fr / Mouse

Lin Chin-I et al.
eNeuro.,  (2019)

publication_link

 

hr_line

Polydopamine-coated gold nanostar for combined antitumor and antiangiogenic therapy in multidrug-resistant breast cancer.

ARG52748: IHC-Fr / Mouse

You You-Hong et al.
Nanotheranostics.,  (2019)

publication_link

 

hr_line

Enhancing Microcirculation on Multitriggering Manner Facilitates Angiogenesis and Collagen Deposition on Wound Healing by Photoreleased NO from Hemin-Derivatized Colloids.

ARG52748: IHC-P / Mouse

Su Chia-Hao et al.
ACS Nano.,  (2019)

publication_link

 

hr_line

Astragaloside IV inhibits lung cancer progression and metastasis by modulating macrophage polarization through AMPK signaling

ARG52748: IHC-P / Mouse

Xu Fei et al.
J Exp Clin Cancer Res.,  (2018)

publication_link

 

hr_line

Stiffness Modification of Photopolymerizable Gelatin-Methacrylate Hydrogels Influences Endothelial Differentiation of Human Mesenchymal Stem Cells.

ARG52748: ICC/IF / Human

Lin Chih-Hsin et al.
J Tissue Eng Regen Med.,  (2018)

publication_link

 

hr_line

Cis-acting circ-CTNNB1 promotes β-catenin signaling and cancer progression via DDX3-mediated transactivation of YY1.

ARG52748: IHC-P / Mouse

Yang Feng et al.
Cancer Res.,  (2018)

publication_link

 

hr_line

Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes.

ARG52748: IHC-P / Mouse

Chen Yajun et al.
Cell Death Differ.,  (2018)

publication_link

 

hr_line

Administration of erythropoietin prevents bone loss in osteonecrosis of the femoral head in mice

ARG52748: IHC-P / Mouse

Taotao Xu et al.
Mol Med Rep.,  (2017)

publication_link

 

hr_line

Obesity enhances carcinogen 7, 12-Dimethylbenz [a] anthracene -induced tumorigenesis in vitro and in vivo.

ARG52748: IHC-P / Mouse

Hsieh Chia-Chien et al.
Food Chem Toxicol.,  (2017)

publication_link

 

hr_line

Injectable bioactive akermanite/alginate composite hydrogels for in situ skin tissue engineering

ARG52748: IHC-Fr / Mouse

Han Y et al.
J. Mater. Chem. B.,  (2017)

publication_link

 

hr_line

Multifunctional Hydrogels Prepared by Dual Ion Cross-Linking for Chronic Wound Healing.

ARG52748: IHC-P / Mouse

Li Y et al.
ACS Appl Mater Interfaces.,  (2017)

publication_link

 

hr_line

CO2 Delivery to Accelerate Incisional Wound Healing Following Single Irradiation of Near-Infrared Lamp on the Coordinated Colloids

ARG52748: IHC-P / Mouse

Wei-Peng Li et al.
ACS Nano. ,  (2017)

publication_link

 

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