Monkey IL1RA ELISA Kit
CAT.NO. : ARG82665
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概述
产品描述 | ARG82665 Monkey IL1RA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Monkey IL1RA in serum, plasma and cell culture supernatants. |
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反应物种 | Mk |
应用 | ELISA |
靶点名称 | IL1RA |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 23.5 pg/ml |
样品类型 | Serum, plasma and cell culture supernatants. |
标准范围 | 46.9 - 3000 pg/ml |
样本量 | 100 µl |
精确 | CV: less than 10% |
別名 | IL1 inhibitor; Interleukin-1 receptor antagonist protein; ICIL-1RA; MVCD4; IL1RA; DIRA; IL-1RN; Anakinra; IL1F3; IRAP; IL-1ra; IL-1ra3 |
应用说明
检测时间 | ~ 3.5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | IL1RN |
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全名 | interleukin 1 receptor antagonist |
背景介绍 | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016] |
生物功能 | Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. [UniProt] |
细胞定位 | Isoform 1: Secreted. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm. [UniProt] |
产品亮点 | Related products: IL1RA antibodies; IL1RA ELISA Kits; IL1RA recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
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