Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC)

产品描述: FITC-conjugated Mouse Monoclonal antibody [4C2] recognizes Human Lambda Light Chain
反应物种: Hu
不反应物种: Goat, Gpig, Hm, Rb, Sheep
应用: FACS
宿主: Mouse
克隆: Monoclonal
克隆号: 4C2
同位型: IgG1
靶点名称: Lambda Light Chain

CAT.NO. : ARG63054

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Size:

100 tests

Product Details

概述

产品描述	FITC-conjugated Mouse Monoclonal antibody [4C2] recognizes Human Lambda Light Chain
反应物种	Hu
不反应物种	Goat, Gpig, Hm, Rb, Sheep
应用	FACS
宿主	Mouse
克隆	Monoclonal
克隆号	4C2
同位型	IgG1
靶点名称	Lambda Light Chain
抗原物种	Human
目标Ig	Human Lambda light chains
偶联标记	FITC
別名	IGL@; IGLC6

应用说明

应用建议

应用	推荐稀释比
FACS	20 µl / 10^6 cells

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化说明	The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
缓冲液	PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA
抗菌剂	15 mM Sodium azide
稳定剂	0.2% (w/v) high-grade protease free BSA
存放说明	Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 3535 Human IGL
基因名称	IGL
全名	immunoglobulin lambda locus
背景介绍	Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq, Jul 2008]
研究领域	Immune System antibody

检测图片 (3)

ARG63054 Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG63054 Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC) (20 µl reagent / 100 µl of peripheral whole blood).
ARG63054 Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC) FACS image
Flow Cytometry: Human lymphocytes stained with ARG63054 Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC) (20 µl reagent / 100 µl of peripheral whole blood) and ARG53782 anti-CD19 antibody [LT19] (APC) (10 µl reagent / 100 µl of peripheral whole blood).
ARG63054 Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC) FACS image
Flow Cytometry: Separation of human Ig lambda light chain positive B-lymphocytes (red-filled) from Ig lambda light chain negative CD19 negative lymphocytes (black-dashed). Human peripheral whole blood stained with ARG63054 Mouse anti-Human Lambda Light Chain antibody [4C2] (FITC) (20 µl reagent / 100 µl of peripheral whole blood).

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