Mouse CDNF recombinant protein (His-tagged, C-ter)
CAT.NO. : ARG70457
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概述
产品描述 | E. coli expressed, His-tagged (C-ter) Mouse CDNF recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | CDNF |
物种 | Mouse |
A.A. 序列 | Gln25 - Leu187 |
表达系统 | E. coli |
Protein Full name | Cerebral dopamine neurotrophic factor |
別名 | CDNF; Cerebral Dopamine Neurotrophic Factor; Conserved Dopamine Neurotrophic Factor; ARMETL1; Arginine-Rich, Mutated In Early Stage Tumors-Like 1; ARMET-Like Protein 1 |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | >98% (by SDS-PAGE) |
缓冲液 | PBS (pH 7.4) |
复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | CDNF |
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全名 | Cerebral Dopamine Neurotrophic Factor |
背景介绍 | Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be active in endoplasmic reticulum and extracellular space. |
生物功能 | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). |
细胞定位 | Secreted |
翻译后修饰 | Disulfide bond |
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