Mouse CLEC7A ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
- 标准范围:
-
Brand:
CAT.NO. : ARG82416
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG82416-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG82416-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG82416-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG82416-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG82416-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG82416-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG82416-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG82416-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG82416-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG82416-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG82416-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG82416 Mouse CLEC7A ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse CLEC7A in serum, plasma (EDTA, heparin) and cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 靶点名称 | CLEC7A |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 50 pg/ml |
| 样品类型 | Serum, plasma (EDTA, heparin) and cell culture supernatants. |
| 标准范围 | 62.5 - 4000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 4.4% Inter-Assay CV: 6.0% |
| 別名 | C-type lectin superfamily member 12; CD369; Dectin-1; Dendritic cell-associated C-type lectin 1; CLECSF12; CANDF4; BGR; Beta-glucan receptor; C-type lectin domain family 7 member A; DC-associated C-type lectin 1; DECTIN1 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q6QLQ4 Mouse C-type lectin domain family 7 member A |
|---|---|
| 基因名称 | CLEC7A |
| 全名 | C-type lectin domain family 7, member A |
| 背景介绍 | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008] |
| 生物功能 | Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity). [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type II membrane protein. Isoform 5: Cytoplasm. Isoform 6: Cytoplasm. Isoform 7: Cytoplasm. [UniProt] |
| 产品亮点 | Related products: CLEC antibodies; CLEC ELISA Kits; CLEC Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Phosphorylated on tyrosine residues in response to glucan binding. [UniProt] |
检测图片 (1)
ARG82416 Mouse CLEC7A ELISA Kit standard curve image
ARG82416 Mouse CLEC7A ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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