Mouse FLT3 Ligand recombinant protein (Active) (His-tagged, C-ter)
Key features and details
- 产品描述:
- 应用:
- 靶点名称:
- 物种:
- A.A. 序列:
- 表达系统:
- 生物活性:
- 活性说明:
- 別名:
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Brand:
CAT.NO. : ARG70187
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Product Details
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Active Mouse FLT3 Ligand recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | FLT3 Ligand |
| 物种 | Mouse |
| A.A. 序列 | Gly27 - Arg188 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce proliferation in BaF3 cells transfected with mouse Flt-3. The ED50 for this effect is |
| 別名 | FLT3L; SL cytokine; Fms-related tyrosine kinase 3 ligand; Flt3L; Flt3 ligand; FL |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | >98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | FLT3LG |
|---|---|
| 全名 | fms-related tyrosine kinase 3 ligand |
| 背景介绍 | Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011] |
| 生物功能 | Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. [UniProt] |
| 细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. [UniProt] |
检测图片 (1)
ARG70187 Mouse FLT3 Ligand recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70187 Mouse FLT3 Ligand recombinant protein (Active) (His-tagged, C-ter).
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