Mouse GAS6 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
-
Brand:
CAT.NO. : ARG82086
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG82086-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG82086-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG82086-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG82086-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG82086-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG82086-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG82086-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG82086-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG82086-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG82086-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG82086-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG82086 Mouse GAS6 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse GAS6 in serum, plasma (heparin, EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | GAS6 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 15.6 pg/ml |
| 样品类型 | Serum, plasma (heparin, EDTA) and cell culture supernatants. |
| 标准范围 | 31.2 - 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 5.3%; Inter-Assay CV: 5.8% |
| 別名 | Growth arrest-specific protein 6; AXLLG; AXSF; GAS-6; AXL receptor tyrosine kinase ligand |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GAS6 |
| 全名 | growth arrest-specific 6 |
| 背景介绍 | This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014] |
| 生物功能 | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: GAS6 antibodies; GAS6 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Isoform 1 is proteolytically processed after secretion to yield a N-terminal 36 kDa protein and a C-terminal 50 kDa protein including the laminin G-like domains which activates AXL. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. [UniProt] |
检测图片 (1)
ARG82086 Mouse GAS6 ELISA Kit standard curve image
ARG82086 Mouse GAS6 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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