Mouse IL5 ELISA kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG80907
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Product Details
概述
| 产品描述 | ARG80907 Mouse IL5 ELISA kit is a Enzyme Immunoassay kit for the quantification of Mouse IL5 in Serum, Plasma, Cell culture supernatants |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | No significant cross-reactivity or interference with GM-CSF, IL3, IL5Rα. |
| 靶点名称 | IL5 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm |
| 灵敏度 | 8 pg/ml |
| 样品类型 | Serum, Plasma, Cell culture supernatants |
| 标准范围 | 15.6 - 1000 pg/ml |
| 样本量 | 100 µl |
| 精确 | CV: less than10% |
| 別名 | Eosinophil differentiation factor; EDF; IL5; TRF; T-cell replacing factor; B-cell differentiation factor I; Interleukin-5 |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | Il5 |
| 全名 | interleukin 5 |
| 背景介绍 | The IL-5 gene is located on chromosome 11 in the mouse, and chromosome 5 in humans, in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Interleukin-5 is also expressed by eosinophils[4] and has been observed in the mast cells of asthmatic airways by immunohistochemistry. IL-5 expression is regulated by several transcription factors including GATA3. [IL-5 wiki] IL5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of IL5 may be related to pathogenesis of eosinophil-dependent inflammatory diseases. IL5 functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). [provided by RefSeq, Jul 2013] |
| 生物功能 | Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. [UniProt] |
| 产品亮点 | Related products: IL5 antibodies; IL5 ELISA Kits; IL5 recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 研究领域 | Cancer kit; Immune System kit |
检测图片 (1)
ARG80907 Mouse IL5 ELISA kit standard curve image
ARG80907 Mouse IL5 ELISA kit results of a typical standard run with optical density reading at 450 nm.
参考文献
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