Mouse MDSC Marker Antibody Duo

Key features and details

  • 产品描述: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells from the myeloid lineage. MDSCs are well-known key negative regulators of the immune response in tumor microenvironment. Accumulated evidences show that MDSCs may serve as a therapeutic target for preventing tumor progression.In mice, MDSCs are defined as cells expressing both CD11b and Gr-1 (Ly6G + Ly6C). arigo’s Mouse MDSC Marker Antibody Duo comprises CD11b and Gr-1 (Ly6G + Ly6C) antibodies. It is the best solution to identify the MDSCs in mouse tumor tissues.Related news:New antibody panels and duos for Tumor immune microenvironmentAnti-SerpinB9 therapy, a new strategy for cancer therapy
  • 靶点名称: Mouse MDSC Marker
  • 別名: Mouse MDSC Marker antibody; Myeloid-derived suppressor cells marker antibody; MDSCs marker antibody; CD11b antibody; Ly6G + Ly6C antibody
  • Brand:
CAT.NO. : ARG30335
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Product Details
内含物
货号内含物名称宿主克隆性反应应用包装
ARG22104anti-Ly6G + Ly6C antibody [RB6-8C5]Rat mAbMsDepletion, FACS, IHC-Fr, IHC-P, IP50 μg
ARG22000anti-CD11b antibody [M1/70]Rat mAbHu, Ms, Bb, R. MkBL, FACS, ICC/IF, IHC-Fr, IP50 μg
概述
产品描述Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells from the myeloid lineage. MDSCs are well-known key negative regulators of the immune response in tumor microenvironment. Accumulated evidences show that MDSCs may serve as a therapeutic target for preventing tumor progression.In mice, MDSCs are defined as cells expressing both CD11b and Gr-1 (Ly6G + Ly6C). arigo’s Mouse MDSC Marker Antibody Duo comprises CD11b and Gr-1 (Ly6G + Ly6C) antibodies. It is the best solution to identify the MDSCs in mouse tumor tissues.

Related news:
New antibody panels and duos for Tumor immune microenvironment
Anti-SerpinB9 therapy, a new strategy for cancer therapy
靶点名称Mouse MDSC Marker
別名Mouse MDSC Marker antibody; Myeloid-derived suppressor cells marker antibody; MDSCs marker antibody; CD11b antibody; Ly6G + Ly6C antibody
属性
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
全名Mouse Myeloid-derived suppressor cell (MDSC) marker Antibody Duo
产品亮点Related products:
MDSC Duos / Panels;
研究领域Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells
检测图片 (2)
  • ARG22000 anti-CD11b antibody [M1/70] IHC-Fr image

    Immunohistochemistry: Cryosection of Mouse lymph node stained with ARG22000 anti-CD11b antibody [M1/70] (green, A) and anti-Mouse CD8 antibody (red, B). Merged image in C.

  • ARG22104 anti-Ly6G + Ly6C antibody [RB6-8C5] IHC-Fr image

    Immunohistochemistry: Mouse spleen section stained with ARG22104 anti-Ly6G + Ly6C antibody [RB6-8C5] followed by ARG21706 Mouse anti-Rat IgG2b antibody [2B10A8] (FITC).

参考文献

Acupuncture promotes neurological recovery and regulates lymphatic function after acute inflammatory nerve root injury

ARG22000: IHC-Fr / Human

Jie Wang et al.
Heliyon.,  (2024)

publication_link

 

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Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation

ARG22000: IHC-Fr, WB / Mouse

Qiu-Yue Lin et al.
BBA - Molecular Basis of Disease,  (2024)

publication_link

 

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Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration

ARG22000:WB / Mouse

Qiu-Yue Lin et al.
Hypertension.,  (2023)

publication_link

 

hr_line

CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization

Mouse / ARG22000: IHC-P, WB

Yun-Long Zhang et al.
J Adv Res.,  (2023)

publication_link

 

hr_line

Downregulation of AKT/mTOR signaling pathway for Salmonella-mediated autophagy in human anaplastic thyroid cancer

ARG22104: IHC-P / Mouse

Li-Hsien Wu et al.
J Cancer,  (2022)

publication_link

 

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