Mouse TNFRSF11B / OPG ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- 灵敏度:
- 样品类型:
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Brand:
CAT.NO. : ARG81667
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Product Details
内含物
| 货号 | 内含物名称 | 包装 | 温度 |
|---|---|---|---|
| ARG81667-001 | Antibody-coated microplate | 8 X 12 strips | 4°C. Unused strips should be sealed tightly in the air-tight pouch. |
| ARG81667-002 | Standard | 2 X 10 ng/vial | 4°C |
| ARG81667-003 | Standard/Sample diluent | 30 ml (Ready to use) | 4°C |
| ARG81667-004 | Antibody conjugate concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81667-005 | Antibody diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81667-006 | HRP-Streptavidin concentrate (100X) | 1 vial (100 µl) | 4°C |
| ARG81667-007 | HRP-Streptavidin diluent buffer | 12 ml (Ready to use) | 4°C |
| ARG81667-008 | 25X Wash buffer | 20 ml | 4°C |
| ARG81667-009 | TMB substrate | 10 ml (Ready to use) | 4°C (Protect from light) |
| ARG81667-010 | STOP solution | 10 ml (Ready to use) | 4°C |
| ARG81667-011 | Plate sealer | 4 strips | Room temperature |
概述
| 产品描述 | ARG81667 Mouse TNFRSF11B / OPG ELISA Kit is an Enzyme Immunoassay kit for the quantification of Mouse TNFRSF11B / OPG in serum, plasma (EDTA) and cell culture supernatants. |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | TNFRSF11B / OPG |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 46.85 pg/ml |
| 样品类型 | Serum, plasma (EDTA) and cell culture supernatants. |
| 标准范围 | 93.7 - 6000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 5.5%; Inter-Assay CV: 6.0% |
| 別名 | OCIF; Osteoclastogenesis inhibitory factor; Tumor necrosis factor receptor superfamily member 11B; PDB5; Osteoprotegerin; OPG; TR1 |
应用说明
| 检测时间 | ~ 5 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # O08712 Mouse Tumor necrosis factor receptor superfamily member 11B |
|---|---|
| 基因名称 | TNFRSF11B |
| 全名 | tumor necrosis factor receptor superfamily, member 11b |
| 背景介绍 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. [UniProt] |
| 产品亮点 | Related products: Osteoprotegerin antibodies; Osteoprotegerin ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | N-glycosylated. Contains sialic acid residues. The N-terminus is blocked. [UniProt] |
检测图片 (1)
ARG81667 Mouse TNFRSF11B / OPG ELISA Kit standard curve image
ARG81667 Mouse TNFRSF11B / OPG ELISA Kit results of a typical standard run with optical density reading at 450 nm.
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