Phospho ATF2 Antibody Panel (Total, pT69, pT71)

Key features and details

  • 产品描述: The activating transcription factor (ATF) and cAMP-response-element binding (CREB) families of transcription factors comprise 16 members of the activator protein 1 (AP1) transcription factor superfamily. ATF and CREB proteins can homodimerize or heterodimerize with members of the Jun, Fos or Maf transcription factor families to form complexes that regulate diverse cellular functions, such as stress responses, embryonic development, disease development and cell death. ATF2 requires phosphorylation by Jun N-terminal kinase (JNK), p38 (MAPK14), or extracellular-signal-regulated kinase 1 (ERK1) at Thr69 and Thr71 residues in order to be transcriptionally active. Lau and Ronai. 2012. J Cell Sci 125:2815 Morton et al. 2004. FEBS Lett 572:177-83 Waas et al. 2001. J Biol Chem 276(8):5676
  • 靶点名称: ATF2
  • 別名: Phospho ATF2 antibody; Phospho Activating transcription factor 2 antibody; ATF2 phospho (Thr69 or 51) antibody; ATF2 phospho (Thr71 or 53) antibody; ATF2 antibody
  • Brand:
CAT.NO. : ARG30227
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Size:
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Product Details
内含物
货号内含物名称宿主克隆性反应应用包装
ARG51535anti-ATF2 phospho (Thr71 or 53) antibodyRabbit pAbHu, Ms, RatIHC-P, WB50 μl
ARG51534anti-ATF2 phospho (Thr69 or 51) antibodyRabbit pAbHu, Ms, RatICC/IF, IHC-P, WB50 μl
ARG63122anti-ATF2 antibodyGoat pAbHuWB50 μg
ARG65351Goat anti-Rabbit IgG antibody (HRP)Goat pAbRbELISA, IHC-P, WB50 μl
ARG65352Donkey anti-Goat IgG antibody (HRP)Donkey pAbGoatELISA, IHC, WB50 μl
概述
产品描述The activating transcription factor (ATF) and cAMP-response-element binding (CREB) families of transcription factors comprise 16 members of the activator protein 1 (AP1) transcription factor superfamily. ATF and CREB proteins can homodimerize or heterodimerize with members of the Jun, Fos or Maf transcription factor families to form complexes that regulate diverse cellular functions, such as stress responses, embryonic development, disease development and cell death. ATF2 requires phosphorylation by Jun N-terminal kinase (JNK), p38 (MAPK14), or extracellular-signal-regulated kinase 1 (ERK1) at Thr69 and Thr71 residues in order to be transcriptionally active. Lau and Ronai. 2012. J Cell Sci 125:2815 Morton et al. 2004. FEBS Lett 572:177-83 Waas et al. 2001. J Biol Chem 276(8):5676
靶点名称ATF2
別名Phospho ATF2 antibody; Phospho Activating transcription factor 2 antibody; ATF2 phospho (Thr69 or 51) antibody; ATF2 phospho (Thr71 or 53) antibody; ATF2 antibody
属性
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
全名Phospho Activating transcription factor 2 (ATF2) Antibody Panel (Total, pT69, pT71)
研究领域Gene Regulation antibody; Immune System antibody
检测图片 (7)
  • ARG51534 anti-ATF2 phospho (Thr69 or 51) antibody WB image

    Western Blot: extracts from 3T3 cells untreated or treated with Anisomycin stained with anti-ATF2 (phospho Thr69 or 51) antibody ARG51534.

  • ARG51534 anti-ATF2 phospho (Thr69 or 51) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-ATF2 (phospho Thr69 or 51) antibody ARG51534 (left) or the same antibody preincubated with blocking peptide (right).

  • ARG51534 anti-ATF2 phospho (Thr69 or 51) antibody ICC/IF image

    Immunofluorescence: methanol-fixed HeLa cells stained with anti-ATF2 (phospho Thr69 or 51) antibody ARG51534.

  • ARG51535 anti-ATF2 phospho (Thr71 or 53) antibody WB image

    Western Blot: extracts from HUVEC cells untreated or treated with Anisomycin stained with anti-ATF2 (phospho Thr71 or 53) antibody ARG51535.

  • ARG51535 anti-ATF2 phospho (Thr71 or 53) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-ATF2 (phospho Thr71 or 53) antibody ARG51535 (left) or the same antibody preincubated with blocking peptide (right).

  • ARG63122 anti-ATF2 antibody WB image

    Western Blot: Human Placenta lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63122 anti-ATF2 antibody at 0.5 µg/ml dilution.

  • ARG63122 anti-ATF2 antibody WB image

    Western Blot: HepG2 (A), K562 (B) and HeLa (C) nuclear lysates (35 µg protein in RIPA buffer) stained with ARG63122 anti-ATF2 antibody at 1 µg/ml dilution.

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