Phospho JunB Antibody Duo (Total, pSer259)

产品描述: JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. Phosphorylation of this residue enhances DNA binding of the JunB/AP-1 complex. Busch, S.J. and Sassone-Corsi, P. (1990) Trends Genet. 6, 36-40. Hess, J. et al. (2004) J. Cell Sci. 117, 5965-5973. Mechta-Grigoriou, F. et al. (2001) Oncogene 20, 2378-2389. Chiu, R. et al. (1989) Cell 59, 979-986.Related news:JunB as a novel gate keeper for prostate cancer progression
靶点名称: JunB
別名: Phospho JunB antibody; JunB phospho (Ser259) antibody; JunB antibody

CAT.NO. : ARG30207

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Size:

1 pair

Product Details

内含物

货号	内含物名称	宿主克隆性	反应	应用	包装
ARG64936	anti-JunB antibody	Goat pAb	Hu	WB	50 μg
ARG51531	anti-JunB phospho (Ser259) antibody	Rabbit pAb	Hu, Ms, Rat	IHC-P, WB	50 μl

概述

产品描述	JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. Phosphorylation of this residue enhances DNA binding of the JunB/AP-1 complex. Busch, S.J. and Sassone-Corsi, P. (1990) Trends Genet. 6, 36-40. Hess, J. et al. (2004) J. Cell Sci. 117, 5965-5973. Mechta-Grigoriou, F. et al. (2001) Oncogene 20, 2378-2389. Chiu, R. et al. (1989) Cell 59, 979-986. Related news: JunB as a novel gate keeper for prostate cancer progression
靶点名称	JunB
別名	Phospho JunB antibody; JunB phospho (Ser259) antibody; JunB antibody

属性

存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名	Antibody Duo for Phospho JunB (Total, pSer259)
研究领域	Gene Regulation antibody

检测图片 (3)

ARG51531 anti-JunB phospho (Ser259) antibody WB image
Western Blot: extracts from HT29 cells untreated or treated with EGF stained with anti-JunB (phospho Ser259) antibody ARG51531.
ARG64936 anti-JUNB antibody WB image
Western Blot: Human Breast Cancer lysate (35 µg protein in RIPA buffer) stained with ARG64936 anti-JunB antibody at 0.3 µg/ml dilution.
ARG51531 anti-JunB phospho (Ser259) antibody IHC-P image
Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-JunB (phospho Ser259) antibody ARG51531 (left) or the same antibody preincubated with blocking peptide (right).

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