Phospho STAT5A Antibody Duo (Total, pY694)

Key features and details

  • 产品描述: STAT5A belongs to STAT family of transcription factors which can be activated by various stimuli such as cytokines and growth factors, including IL-2, GM-CSF, Erythropoietin and Thrombopoietin. The phosphorylation of STAT5A at Tyr694 residue by SRS Kinase upon Erythropoietin stimulation triggers its activation and is responsible for EPO-induced signal transduction. STAT5A phosphorylation can also be induced by Prolactin to increase its DNA binding and transcription ability. Lin and Leonard. 2000. Oncogene 19(21):2566 Okutani et al. 2001. Oncogene 20(45):6643 Gouilleux et al. 1994. EMBO J 13(18):4361-9
  • 靶点名称: STAT5A
  • 別名: Phospho STAT5A antibody; Phospho Signal transducer and activator of transcription 5A antibody; STAT5A phospho (Tyr694) antibody; STAT5A antibody
  • Brand:
CAT.NO. : ARG30214
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Product Details
内含物
货号内含物名称宿主克隆性反应应用包装
ARG51552anti-STAT5A phospho (Tyr694) antibodyRabbit pAbHu, Ms, RatIHC-P, WB50 μl
ARG65593anti-STAT5A antibodyRabbit pAbHuIHC-P, WB50 μl
概述
产品描述STAT5A belongs to STAT family of transcription factors which can be activated by various stimuli such as cytokines and growth factors, including IL-2, GM-CSF, Erythropoietin and Thrombopoietin. The phosphorylation of STAT5A at Tyr694 residue by SRS Kinase upon Erythropoietin stimulation triggers its activation and is responsible for EPO-induced signal transduction. STAT5A phosphorylation can also be induced by Prolactin to increase its DNA binding and transcription ability. Lin and Leonard. 2000. Oncogene 19(21):2566 Okutani et al. 2001. Oncogene 20(45):6643 Gouilleux et al. 1994. EMBO J 13(18):4361-9
靶点名称STAT5A
別名Phospho STAT5A antibody; Phospho Signal transducer and activator of transcription 5A antibody; STAT5A phospho (Tyr694) antibody; STAT5A antibody
属性
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
全名Phospho Signal transducer and activator of transcription 5A (STAT5A) Antibody Duo (Total, pY694)
研究领域Gene Regulation antibody; Signaling Transduction antibody
检测图片 (4)
  • ARG51552 anti-STAT5A phospho (Tyr694) antibody WB image

    Western Blot: extracts from K562 cells untreated or treated with G-CSF stained with anti-STAT5A (phospho Tyr694) antibody ARG51552.

  • ARG51552 anti-STAT5A phospho (Tyr694) antibody IHC-P image

    Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-STAT5A (phospho Tyr694) antibody ARG51552 (left) or the same antibody preincubated with blocking peptide (right).

  • ARG65593 anti-STAT5A Antibody IHC-P image

    Immunohistochemistry: paraffin-embedded Human breast carcinoma tissue stained with ARG65593 (STAT5A Antibody) at 1/50 dilution, or the same antibody preincubated with synthetic peptide (right). (Original magnification: ×200)

  • ARG65593 anti-STAT5A Antibody WB image

    Western Blot: ARG65593 STAT5A Antibody at 1/500 dilution with 30 μg of lysates.
    (1) HeLa cell
    (2) K562 cell

    Exposure time: 1 minute.

参考文献

Effects of di (2-ethylhexyl) phthalate and high-fat diet on lipid metabolism in rats by JAK2/STAT5.

ARG51552: WB / Rat

Zhang Yuezhu et al.
Environ Sci Pollut Res Int.,  (2019)

publication_link

 

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Mono-2-ethylhexyl phthalate (MEHP) promoted lipid accumulation via JAK2/STAT5 and aggravated oxidative stress in BRL-3A cells.

ARG51552: WB / Rat

Zhang Yuezhu et al.
Ecotoxicol Environ Saf.,  (2019)

publication_link

 

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