Porcine IL10 ELISA Kit
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 靶点名称:
- 偶联标记:
- 偶联标记说明:
- Protein Full name:
- 灵敏度:
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Brand:
CAT.NO. : ARG83026
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Size:
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Product Details
概述
| 产品描述 | ARG83026 Porcine IL10 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Porcine IL10 in serum, plasma (heparin), ascites, urine and cell culture supernatants. |
|---|---|
| 反应物种 | Pig |
| 应用 | ELISA |
| 特异性 | Not cross-reacts with: Human IL-4, porcine, IFN gamma. Mouse IL-4, porcine, IFN gamma. Rat IL-4, porcine, IFN gamma. |
| 靶点名称 | IL10 |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| Protein Full name | Interleukin 10 |
| 灵敏度 | 23.44 pg/ml |
| 样品类型 | Serum, plasma (heparin), ascites, urine and cell culture supernatants. |
| 标准范围 | 46.875 - 3000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | IL10, Interleukin 10 ,IL 10, CSIF, Cytokine Synthesis Inhibitory Factor, IL10A, TGIF, T Cell Growth Inhibitory Factor, Interleukin 10, GVHDS |
应用说明
| 检测时间 | ~ 4 hours |
|---|
属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL10 |
| 全名 | Interleukin 10 |
| 背景介绍 | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020] |
| 生物功能 | Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: IL10 antibodies; IL10 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
检测图片 (1)
ARG83026 Porcine IL10 ELISA Kit standard curve image
ARG83026Porcine IL10 ELISA Kit results of standard run with optical density reading at 450 nm
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