Rabbit Activin A ELISA Kit
CAT.NO. : ARG83116
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概述
产品描述 | ARG83116 Rabbit Activin A ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rabbit Activin A in Serum, Plasma, Saliva, Cell culture supernatants. |
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反应物种 | Rb |
应用 | ELISA |
特异性 | There is no detectable cross-reactivity with other relevant proteins. |
靶点名称 | Activin A |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | less than 12 pg/ml |
检测范围 | 15.6 pg/ml - 1,000 pg/ml |
样品类型 | Serum, Plasma, Saliva, Cell culture supernatants |
精确 | Intra-Assay CV: 5.6% Inter-Assay CV: 6.6% |
別名 | Erythroid differentiation protein; Activin beta-A chain; FRP; EDF; Inhibin beta A chain |
应用说明
检测时间 | ~ 5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | INHBA |
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全名 | inhibin, beta A |
背景介绍 | The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. |
生物功能 | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
细胞定位 | Secreted. |
产品亮点 | Related products: Activin A antibodies; Activin A ELISA Kits; Activin A recombinant proteins; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
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