Rabbit C Reactive Protein ELISA Kit
CAT.NO. : ARG83494
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概述
产品描述 | ARG83494 Rabbit C Reactive Protein ELISA Kit is an Enzyme Immunoassay kit for the quantification of Rabbit C Reactive Protein in Plasma and Serum |
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反应物种 | Rb |
应用 | ELISA |
靶点名称 | C Reactive Protein |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 3 ng/ml |
样品类型 | Plasma and Serum |
标准范围 | 6.25 - 200 ng/ml |
样本量 | 100 µl |
精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
別名 | CRP; C-Reactive Protein; PTX1; C-Reactive Protein, Pentraxin-Related; Pentraxin 1 |
应用说明
检测时间 | 0.5 hour |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | CRP |
全名 | C-reactive protein, pentraxin-related |
背景介绍 | The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. |
生物功能 | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
细胞定位 | Secreted |
翻译后修饰 | Disulfide bond, Pyrrolidone carboxylic acid |
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