SARS-CoV-2 Spike recombinant protein (S1 Subunit) (His-tagged, C-ter)

Key features and details

  • 产品描述: E. coli expressed, His-tagged (C-ter) SARS-CoV-2 Spike recombinant protein (S1 Subunit)
  • 应用: SDS-PAGE
  • 靶点名称: SARS-CoV-2 Spike protein (S1 Subunit)
  • 物种: Virus
  • A.A. 序列: Val16 - Cys671
  • 表达系统: E. coli
  • Brand:
CAT.NO. : ARG70218
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Product Details
概述
产品描述E. coli expressed, His-tagged (C-ter) SARS-CoV-2 Spike recombinant protein (S1 Subunit)
应用SDS-PAGE
靶点名称SARS-CoV-2 Spike protein (S1 Subunit)
物种Virus
A.A. 序列Val16 - Cys671
表达系统E. coli
属性
形式Powder
纯度>98% (by SDS-PAGE)
缓冲液PBS (pH 8.0)
复溶It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
存放说明For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项For laboratory research only, not for drug, diagnostic or other use.
检测图片 (1)
  • ARG70218 SARS-CoV-2 Spike recombinant protein (S1 Subunit) (His-tagged, C-ter) SDS-PAGE image

    SDS-PAGE analysis of ARG70218 SARS-CoV-2 Spike recombinant protein (S1 Subunit) (His-tagged, C-ter).

参考文献

Cytokines from SARS-CoV-2 Spike-Activated Macrophages Hinder Proliferation and Cause Cell Dysfunction in Endothelial Cells

Functional assay / 

Giulia Recchia Luciani et al.
Biomolecules.,  (2024)

publication_link

 

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Cytokine-Induced iNOS in A549 Alveolar Epithelial Cells: A Potential Role in COVID-19 Lung Pathology

Functional assay / 

Amelia Barilli et al.
Biomedicines.,  (2023)

publication_link

 

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Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2

Functional assay / 

Kyong-Su Park et al.
J Nanobiotechnology.,  (2023)

publication_link

 

hr_line

Growth Arrest of Alveolar Cells in Response to Cytokines from Spike S1-Activated Macrophages: Role of IFN-γ

Functional assay / Human

Amelia Barilli et al.
Biomedicines,  (2022)

publication_link

 

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The JAK1/2 Inhibitor Baricitinib Mitigates the Spike-Induced Inflammatory Response of Immune and Endothelial Cells In Vitro

Amelia Barilli et al.
Biomedicines,  (2022)

publication_link

 

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SARS-CoV-2 Spike protein is not pro-inflammatory in human primary macrophages: endotoxin contamination and lack of protein glycosylation as possible confounders

Functional Assay / Virus

Gloria Cinquegrani et al.
Cell Biol Toxicol.,  (2022)

publication_link

 

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Immune-Mediated Inflammatory Responses of Alveolar Epithelial Cells: Implications for COVID-19 Lung Pathology

Functional assay / 

Amelia Barilli et al.
Biomedicines.,  (2022)

publication_link

 

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In Vitro Exposure of Primary Human T Cells and Monocytes to Polyclonal Stimuli Reveals a Basal Susceptibility to Display an Impaired Cellular Immune Response and Develop Severe COVID-19

Cell Stimulation / 

Rebeca Viurcos-Sanabria et al.
Front Immunol.,  (2022)

publication_link

 

hr_line

Standardized Extract of Asparagus officinalis Stem Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages

Functional assay / Virus

Ken Shirato et al.
Molecules,  (2021)

publication_link

 

hr_line

Endothelial Cell Activation by SARS-CoV-2 Spike S1 Protein: A Crosstalk between Endothelium and Innate Immune Cells

Stimulation  / 

Bianca Maria Rotoli et al.
Biomedicines.,  (2021)

publication_link

 

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ETAS®50 Attenuates SARS-CoV-2 Spike Protein-Induced IL-6 and IL-1β Production by Suppressing p44/42 MAPK and Akt Phosphorylation in Murine Primary Macrophages.

Ken Shirato et al.
Preprint.,  (2021)

publication_link

 

hr_line

SARS-CoV-2 spike protein S1 subunit induces pro-inflammatory responses via toll-like receptor 4 signaling in murine and human macrophages

Stimulation / 

Ken Shirato et al.
Heliyon.,  (2021)

publication_link

 

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